The Aurelia used the first production V6 engine, a 60° design developed by de Virgilio, a Lancia engineer who worked under Jano which grew from 1.8 L to 2.5 L. It was an all-alloy pushrod design with a single camshaft between the cylinder banks. A hemispherical combustion chamber and inline valves were used. A single Weber 40 carburettor completed the engine.
At the rear was an innovative combination transaxle with the gearbox, clutch, differential, and inboard-mounted drum brakes. The front suspension was a sliding pillar design, with rear semi-trailing arms replaced by a de Dion tube in the Fourth series.